Amylase from Streptococcus pyogenes inhibits biofilm formation in Streptococcus salivarius

نویسندگان

چکیده

Biofilms are extracellular constituents composed of polysaccharides and other substances necessary for bacteria to defend themselves against foreign enemies. Amylase Streptococcus pyogenes is an enzyme that degrades produces nutrients invasion epithelial cells. S. salivarius oral commensal bacterium shows antibacterial activity pyogenes. We investigated the relationship between determine whether amylase affects biofilm salivarius. The amyA gene-deficient strains were generated from 1529 MDYK strains, production ability wild-type compared. in mutant strain was significantly reduced compared strain. Next, biofilm-forming increased observed strains. cultured create biofilms, then added culture. Significantly, biofilms with higher than those wild As co-cultured compared, also increased. These results common findings Our suggest inhibits formation

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ژورنال

عنوان ژورنال: GSC Advanced Research and Reviews

سال: 2023

ISSN: ['2582-4597']

DOI: https://doi.org/10.30574/gscarr.2023.14.2.0050